ACE-031
Also known as: ace031, ramatercept, ACVR2B-Fc
Soluble ActRIIB decoy receptor studied for inhibiting myostatin pathway to increase muscle mass.
Quick Reference
ACE-031 - Research Images
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Overview
A decoy receptor is a receptor that is able to recognize and bind specific ligands efficiently, but is not able to support its intended function. This ligand can be a growth factors or cytokines, in which case the receptor is not structurally able to signal or activate the intended receptor complex. It can also be a pathogen, preventing normal cell attachment or cell entry. In either case it acts as an inhibitor, binding a ligand and keeping it from binding to its regular receptor. Decoy receptors participate in common methods of signal inhibition and are also abundant in malignant tissues, making up a significant topic in cancer research.
Mechanism of Action
A decoy receptor is a receptor that is able to recognize and bind specific ligands efficiently, but is not able to support its intended function. This ligand can be a growth factors or cytokines, in which case the receptor is not structurally able to signal or activate the intended receptor complex. It can also be a pathogen, preventing normal cell attachment or cell entry. In either case it acts as an inhibitor, binding a ligand and keeping it from binding to its regular receptor. Decoy receptors participate in common methods of signal inhibition and are also abundant in malignant tissues, making up a significant topic in cancer research.
What Researchers Are Saying
Community Reports - Not Medical Advice
The following is aggregated from public forums, Reddit, and research communities. These are anecdotal reports from researchers only - not verified clinical data and not a recommendation of any kind.
ACE-031 (also known as ace031, ramatercept) is studied within the growth hormone axis and body composition research community. Soluble ActRIIB decoy receptor studied for inhibiting myostatin pathway to increase muscle mass.
Last updated October 28, 2026
Research status: limited. ACE-031 appears across growth hormone axis and body composition research forums and academic literature. Researchers note this compound falls in the growth hormone category.
Last updated October 28, 2026
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