Acetyl Hexapeptide-3
Also known as: Argireline, AH3, acetyl hexapeptide-8, argireline, SNAP-25 analogue
SNAP-25 inhibitor peptide studied for its effects on facial muscle contraction and skin smoothing in cosmetic research.
Quick Reference
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Overview
Chemical compound
Acetyl hexapeptide-8, also known as acetyl hexapeptide-8 amide and Argireline, is a synthetic hexapeptide used as a topical cosmetic ingredient that may improve the appearance of wrinkles. It is a small peptide fragment of SNAP25, a protein involved in neurotransmitter release and one of the targets of botulinum toxin type A, commonly known as Botox.
Mechanism of Action
Acetyl hexapeptide-8, also known as acetyl hexapeptide-8 amide and Argireline, is a synthetic hexapeptide used as a topical cosmetic ingredient that may improve the appearance of wrinkles. It is a small peptide fragment of SNAP25, a protein involved in neurotransmitter release and one of the targets of botulinum toxin type A, commonly known as Botox.
What Researchers Are Saying
Community Reports - Not Medical Advice
The following is aggregated from public forums, Reddit, and research communities. These are anecdotal reports from researchers only - not verified clinical data and not a recommendation of any kind.
Acetyl Hexapeptide-3 (also known as Argireline, AH3) is studied within the dermatology and hair growth research community. SNAP-25 inhibitor peptide studied for its effects on facial muscle contraction and skin smoothing in cosmetic research.
Last updated October 28, 2026
Research status: active. Acetyl Hexapeptide-3 appears across dermatology and hair growth research forums and academic literature. Researchers note this compound falls in the hair skin category.
Last updated October 28, 2026
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