Angiotensin 1-7
Also known as: ang 1-7, ang(1-7), alamandine precursor
Angiotensin-(1-7) is a seven-amino-acid peptide in the renin-angiotensin system, which regulates blood pressure and fluid balance. It acts as a counter-regulatory entity in this system, with effects typically opposing those of angiotensin II, the system's primary vasoconstrictive signal.
Quick Reference
Angiotensin 1-7 - Research Images
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Mechanism of Action
Angiotensin-(1-7) is generated by enzymatic cleavage of angiotensin I or angiotensin II and primarily signals through the Mas receptor. It is associated with opposing effects to angiotensin II, such as vasodilation and anti-inflammatory actions in tissue studies. Due to its rapid clearance from circulation, research often focuses on its production pathways and receptor interactions rather than its direct presence as a stable circulating peptide.
Research History
The renin-angiotensin system was long dominated by the study of angiotensin II until angiotensin-(1-7) was identified as a distinct bioactive molecule in the late 1980s. A pivotal 2005 review highlighted its significance, coinciding with discoveries that ACE inhibitors can markedly increase its levels in the bloodstream. Subsequent research linked it to the Mas receptor and explored its associations with inflammation and tissue repair.
What Researchers Are Saying
Community Reports - Not Medical Advice
The following is aggregated from public forums, Reddit, and research communities. These are anecdotal reports from researchers only - not verified clinical data and not a recommendation of any kind.
Angiotensin 1-7 (also known as ang 1-7, ang(1-7)) is studied within the peptide research community. Vasoactive heptapeptide studied for cardiovascular protection and counter-regulation of the angiotensin axis.
Last updated October 28, 2026
Research status: active. Angiotensin 1-7 appears across peptide research forums and academic literature. Researchers note this compound falls in the other category.
Last updated October 28, 2026
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