Fibronectin III
Also known as: FNIII, fibronectin type III domain, FN3
Extracellular matrix domain peptide studied for cell adhesion, wound healing, and tissue engineering applications.
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Overview
Protein domain
The Fibronectin type III domain is an evolutionarily conserved protein domain that is widely found in animal proteins. The fibronectin protein in which this domain was first identified contains 16 copies of this domain. The domain is about 100 amino acids long and possesses a beta sandwich structure. Of the three fibronectin-type domains, type III is the only one without disulfide bonding present. Fibronectin domains are found in a wide variety of extracellular proteins. They are widely distributed in animal species, but also found sporadically in yeast, plant and bacterial proteins.
Mechanism of Action
The Fibronectin type III domain is an evolutionarily conserved protein domain that is widely found in animal proteins. The fibronectin protein in which this domain was first identified contains 16 copies of this domain. The domain is about 100 amino acids long and possesses a beta sandwich structure. Of the three fibronectin-type domains, type III is the only one without disulfide bonding present. Fibronectin domains are found in a wide variety of extracellular proteins. They are widely distributed in animal species, but also found sporadically in yeast, plant and bacterial proteins.
What Researchers Are Saying
Community Reports - Not Medical Advice
The following is aggregated from public forums, Reddit, and research communities. These are anecdotal reports from researchers only - not verified clinical data and not a recommendation of any kind.
Fibronectin III (also known as FNIII, fibronectin type III domain) is studied within the tissue repair and recovery research community. Extracellular matrix domain peptide studied for cell adhesion, wound healing, and tissue engineering applications.
Last updated October 28, 2026
Research status: emerging. Fibronectin III appears across tissue repair and recovery research forums and academic literature. Researchers note this compound falls in the tissue repair category.
Last updated October 28, 2026
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