Gastrin
Also known as: gastrin-17, gastrin-34, big gastrin
Gastrin is a stomach hormone peptide produced by G cells, best known for prompting the stomach lining to release hydrochloric acid. UniProt records its larger 34 amino acid form, while shorter forms such as gastrin-17 are also widely referenced in physiology research.
Quick Reference
Gastrin - Research Images
PSO vial render · Scientific images from Wikipedia · Tap to enlarge
Overview
Mammalian protein found in Homo sapiens
Gastrin is a peptide hormone that stimulates secretion of gastric acid (HCl) by the parietal cells of the stomach and aids in gastric motility. It is released by G cells in the pyloric antrum of the stomach, duodenum, and the pancreas.
Mechanism of Action
Gastrin prompts tissue in the stomach mucosa to make and release hydrochloric acid, and it signals the pancreas to release digestive enzymes. It also encourages smooth muscle contraction and raises blood flow and water movement in the stomach and intestine. Its receptor, CCKBR, is the same receptor used by cholecystokinin.
Research History
Gastrin entered physiology as the hormone signal linking food intake to acid release in the stomach. Research since then has followed its forms of different lengths, its receptor CCKBR, and its appearances outside the stomach, including in developmental biology.
What Researchers Are Saying
Community Reports - Not Medical Advice
The following is aggregated from public forums, Reddit, and research communities. These are anecdotal reports from researchers only - not verified clinical data and not a recommendation of any kind.
Gastrin (also known as gastrin-17, gastrin-34) is studied within the peptide research community. Gastric acid-stimulating peptide produced by G cells; studied in acid-secretion models and gastric physiology research.
Last updated October 28, 2026
Research status: active. Gastrin appears across peptide research forums and academic literature. Researchers note this compound falls in the other category.
Last updated October 28, 2026
What Do You Think of This Peptide?
Share your opinion or research experience with Gastrin. Comments are reviewed before appearing.