Macimorelin
Also known as: AEZS-130, ghrelin receptor agonist macimorelin
Oral ghrelin receptor agonist studied as diagnostic agent for adult GH deficiency with favorable safety profile.
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Overview
Chemical compound
Macimorelin (INN) – or Macrilen – is a drug that was developed by Aeterna Zentaris for use in the diagnosis of adult growth hormone deficiency. Macimorelin acetate, the salt formulation, is a synthetic growth hormone secretagogue receptor agonist. It is a growth hormone secretagogue receptor agonist, causing release of growth hormone from the pituitary gland. Macimorelin acetate is described chemically as D-Tryptophanamide, 2-methylalanyl-N-[(1R)-1-(formylamino)-2-(1H-indol-3-yl)ethyl]-acetate.
Mechanism of Action
Macimorelin (INN) – or Macrilen – is a drug that was developed by Aeterna Zentaris for use in the diagnosis of adult growth hormone deficiency. Macimorelin acetate, the salt formulation, is a synthetic growth hormone secretagogue receptor agonist. It is a growth hormone secretagogue receptor agonist, causing release of growth hormone from the pituitary gland. Macimorelin acetate is described chemically as D-Tryptophanamide, 2-methylalanyl-N-[(1R)-1-(formylamino)-2-(1H-indol-3-yl)ethyl]-acetate.
What Researchers Are Saying
Community Reports - Not Medical Advice
The following is aggregated from public forums, Reddit, and research communities. These are anecdotal reports from researchers only - not verified clinical data and not a recommendation of any kind.
Macimorelin (also known as AEZS-130, ghrelin receptor agonist macimorelin) is studied within the growth hormone axis and body composition research community. Oral ghrelin receptor agonist studied as diagnostic agent for adult GH deficiency with favorable safety profile.
Last updated October 28, 2026
Research status: active. Macimorelin appears across growth hormone axis and body composition research forums and academic literature. Researchers note this compound falls in the growth hormone category.
Last updated October 28, 2026
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