P21
Also known as: p21 peptide, cilliary neurotrophic factor analogue, CNTF peptide
CNTF-derived peptide studied for neurogenesis, BDNF elevation, and cognitive enhancement.
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P21 - Research Images
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Overview
Protein
p21Cip1, also known as cyclin-dependent kinase inhibitor 1 or CDK-interacting protein 1, is a cyclin-dependent kinase inhibitor (CKI) that is capable of inhibiting all cyclin/CDK complexes, though is primarily associated with inhibition of CDK2. p21 represents a major target of p53 activity and thus is associated with linking DNA damage to cell cycle arrest. This protein is encoded by the CDKN1A gene located on chromosome 6 (6p21.2) in humans.
Mechanism of Action
p21Cip1, also known as cyclin-dependent kinase inhibitor 1 or CDK-interacting protein 1, is a cyclin-dependent kinase inhibitor (CKI) that is capable of inhibiting all cyclin/CDK complexes, though is primarily associated with inhibition of CDK2. p21 represents a major target of p53 activity and thus is associated with linking DNA damage to cell cycle arrest. This protein is encoded by the CDKN1A gene located on chromosome 6 (6p21.2) in humans.
What Researchers Are Saying
Community Reports - Not Medical Advice
The following is aggregated from public forums, Reddit, and research communities. These are anecdotal reports from researchers only - not verified clinical data and not a recommendation of any kind.
P21 (also known as p21 peptide, cilliary neurotrophic factor analogue) is studied within the cognitive function and neuroprotection research community. CNTF-derived peptide studied for neurogenesis, BDNF elevation, and cognitive enhancement.
Last updated October 28, 2026
Research status: emerging. P21 appears across cognitive function and neuroprotection research forums and academic literature. Researchers note this compound falls in the cognitive category.
Last updated October 28, 2026
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