Palmitoyl Pentapeptide-4
Also known as: matrixyl, palmitoyl pentapeptide 4, pal-KTTKS, lysyl-threonyl-threonyl-lysyl-serine, palmitoyl KTTKS
Signal peptide studied for collagen and fibronectin synthesis in aged skin.
Quick Reference
Palmitoyl Pentapeptide-4 - Research Images
PSO vial render · Scientific images from Wikipedia · Tap to enlarge
Overview
Chemical compound
Palmitoyl pentapeptide-4 is a matrikine used in anti-wrinkle cosmetics. It was launched in 2000 as an active ingredient for the personal care industry under the trade name Matrixyl by the French cosmetic active ingredient manufacturer Sederma SAS.
Mechanism of Action
Palmitoyl pentapeptide-4 is a matrikine used in anti-wrinkle cosmetics. It was launched in 2000 as an active ingredient for the personal care industry under the trade name Matrixyl by the French cosmetic active ingredient manufacturer Sederma SAS.
What Researchers Are Saying
Community Reports - Not Medical Advice
The following is aggregated from public forums, Reddit, and research communities. These are anecdotal reports from researchers only - not verified clinical data and not a recommendation of any kind.
Palmitoyl Pentapeptide-4 (also known as matrixyl, palmitoyl pentapeptide 4) is studied within the longevity and anti-aging research community. Signal peptide studied for collagen and fibronectin synthesis in aged skin.
Last updated October 28, 2026
Research status: active. Palmitoyl Pentapeptide-4 appears across longevity and anti-aging research forums and academic literature. Researchers note this compound falls in the anti aging category.
Last updated October 28, 2026
What Do You Think of This Peptide?
Share your opinion or research experience with Palmitoyl Pentapeptide-4. Comments are reviewed before appearing.