Setmelanotide
Also known as: RM-493, imcivree, MC4R agonist
MC4 receptor agonist studied for severe genetic obesity, particularly POMC and LEPR deficiencies.
Quick Reference
Setmelanotide - Research Images
PSO vial render · Scientific images from Wikipedia · Tap to enlarge
Overview
Chemical compound
Setmelanotide, sold under the brand name Imcivree, is a medication used for the treatment of genetic obesity caused by a rare single-gene mutation.
Mechanism of Action
Setmelanotide, sold under the brand name Imcivree, is a medication used for the treatment of genetic obesity caused by a rare single-gene mutation.
What Researchers Are Saying
Community Reports - Not Medical Advice
The following is aggregated from public forums, Reddit, and research communities. These are anecdotal reports from researchers only - not verified clinical data and not a recommendation of any kind.
Setmelanotide (also known as RM-493, imcivree) is studied within the metabolic health research community. MC4 receptor agonist studied for severe genetic obesity, particularly POMC and LEPR deficiencies.
Last updated October 28, 2026
Research status: active. Setmelanotide appears across metabolic health research forums and academic literature. Researchers note this compound falls in the metabolic category.
Last updated October 28, 2026
What Do You Think of This Peptide?
Share your opinion or research experience with Setmelanotide. Comments are reviewed before appearing.