Somatostatin
Also known as: SRIF, growth hormone inhibiting hormone, somatotropin release inhibiting factor, SST, growth hormone release-inhibiting factor
Cyclic peptide that inhibits GH secretion; studied for neuroendocrine tumor and acromegaly treatment.
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Overview
Peptide hormone that regulates the endocrine system
Somatostatin, also known as growth hormone-inhibiting hormone (GHIH) or by several other names, is a peptide hormone that regulates the endocrine system and affects neurotransmission and cell proliferation via interaction with G protein-coupled somatostatin receptors and inhibition of the release of numerous secondary hormones. Somatostatin inhibits insulin and glucagon secretion.
Mechanism of Action
Somatostatin, also known as growth hormone-inhibiting hormone (GHIH) or by several other names, is a peptide hormone that regulates the endocrine system and affects neurotransmission and cell proliferation via interaction with G protein-coupled somatostatin receptors and inhibition of the release of numerous secondary hormones. Somatostatin inhibits insulin and glucagon secretion.
What Researchers Are Saying
Community Reports - Not Medical Advice
The following is aggregated from public forums, Reddit, and research communities. These are anecdotal reports from researchers only - not verified clinical data and not a recommendation of any kind.
Somatostatin (also known as SRIF, growth hormone inhibiting hormone) is studied within the growth hormone axis and body composition research community. Cyclic peptide that inhibits GH secretion; studied for neuroendocrine tumor and acromegaly treatment.
Last updated October 28, 2026
Research status: active. Somatostatin appears across growth hormone axis and body composition research forums and academic literature. Researchers note this compound falls in the growth hormone category.
Last updated October 28, 2026
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