Also known as: ta65, cycloastragenol, telomerase activator 65
Plant-derived small molecule studied for telomerase activation and cellular senescence reduction.

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Chemical compound
Cycloastragenol is a triterpenoid isolated from various legume species in the genus Astragalus that is purported to have telomerase activation activity. A preliminary in vitro study on human CD4 and CD8 T cells found that cycloastragenol may moderately increase telomerase activity and inhibit the onset of cellular senescence.
Cycloastragenol is a triterpenoid isolated from various legume species in the genus Astragalus that is purported to have telomerase activation activity. A preliminary in vitro study on human CD4 and CD8 T cells found that cycloastragenol may moderately increase telomerase activity and inhibit the onset of cellular senescence.
Community Reports - Not Medical Advice
The following is aggregated from public forums, Reddit, and research communities. These are anecdotal reports from researchers only - not verified clinical data and not a recommendation of any kind.
TA-65 (also known as ta65, cycloastragenol) is studied within the longevity and anti-aging research community. Plant-derived small molecule studied for telomerase activation and cellular senescence reduction.
Last updated October 28, 2026
Research status: active. TA-65 appears across longevity and anti-aging research forums and academic literature. Researchers note this compound falls in the anti aging category.
Last updated October 28, 2026
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