YK-11
Also known as: YK11, myostatin inhibitor YK-11
Steroidal SARM and partial myostatin inhibitor studied for supraphysiological anabolic effects in muscle models.
Quick Reference
YK-11 - Research Images
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Overview
Steroid drug
YK-11 is a synthetic steroidal selective androgen receptor modulator (SARM). It is a gene-selective partial agonist of the androgen receptor (AR) and does not induce the physical interaction between the NTD/AF1 and LBD/AF2, which is required for full transactivation of the AR. The drug has anabolic activity in vitro in C2C12 myoblasts and shows greater potency than dihydrotestosterone (DHT) in this regard. It has been investigated as a potential treatment for sepsis-induced muscle wasting in animal studies. YK-11 has been encountered as a novel designer drug.
Mechanism of Action
YK-11 is a synthetic steroidal selective androgen receptor modulator (SARM). It is a gene-selective partial agonist of the androgen receptor (AR) and does not induce the physical interaction between the NTD/AF1 and LBD/AF2, which is required for full transactivation of the AR. The drug has anabolic activity in vitro in C2C12 myoblasts and shows greater potency than dihydrotestosterone (DHT) in this regard. It has been investigated as a potential treatment for sepsis-induced muscle wasting in animal studies. YK-11 has been encountered as a novel designer drug.
What Researchers Are Saying
Community Reports - Not Medical Advice
The following is aggregated from public forums, Reddit, and research communities. These are anecdotal reports from researchers only - not verified clinical data and not a recommendation of any kind.
YK-11 (also known as YK11, myostatin inhibitor YK-11) is studied within the selective androgen receptor research community. Steroidal SARM and partial myostatin inhibitor studied for supraphysiological anabolic effects in muscle models.
Last updated October 28, 2026
Research status: limited. YK-11 appears across selective androgen receptor research forums and academic literature. Researchers note this compound falls in the sarms category.
Last updated October 28, 2026
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