Bombesin
Also known as: BBS · amphibian bombesin · GRP analogue
For in-vitro (laboratory) research purposes only. Not for human or animal consumption.
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For in-vitro research use only. Not for human consumption.
1What Is Bombesin?
Amphibian neuropeptide related to human GRP; studied as tumor-targeting vector for GRP receptor-positive cancers.
4Published Research - Plain English Summaries
The studies below have been published in peer-reviewed journals. Summaries are written in plain language - no jargon. Citations are provided as text only.
Key finding: The authors note peptide instability in the body is the main limitation the knottin modification addresses.
A 2024 paper described bombesin-based radiopharmaceutical precursors stabilized with a knottin scaffold.
Beloborodov EA, Iurova EV, Fomin AN, Saenko YV · 2024 · Sovremennye tekhnologii v meditsine · PMID 39539754
Key finding: The review describes antibody and peptide-conjugated chemotherapy as recent advances in this area.
A 2022 review covered bombesin-drug conjugates as targeting vehicles in small cell lung cancer research.
Zhang Y, Holland E, Dinh A, Au D, Sun L · 2022 · American journal of cancer research · PMID 35411251
Key finding: The review reports that blocking gastrin receptors negated the gastroprotective effect in the cited models.
A 2005 review examined how bombesin protects the stomach lining in animal models, mainly through gastrin release.
West SD, Mercer DW · 2005 · Annals of surgery · PMID 15650631
Key finding: The review names hypothalamic nuclei and the dorsal vagal complex among bombesin-responsive sites.
A 2000 review covered bombesin's actions in the brain-gut axis, including responsive sites in the hypothalamus and brainstem.
Martinez V, Taché Y · 2000 · Peptides · PMID 11090915
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All content on this page is for in-vitro research purposes only. Not intended for human or animal use. Consult a licensed professional before handling research chemicals. No content on this page constitutes medical advice or a treatment recommendation.
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