Difelikefalin
Also known as: CR845 · kappa opioid agonist · kappa opioid peptide peripherally restricted
For in-vitro (laboratory) research purposes only. Not for human or animal consumption.
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For in-vitro research use only. Not for human consumption.
1What Is Difelikefalin?
Peripherally restricted kappa-opioid receptor agonist studied for pruritus and inflammation without central side effects.
4Published Research - Plain English Summaries
The studies below have been published in peer-reviewed journals. Summaries are written in plain language - no jargon. Citations are provided as text only.
Larsen GØ, Kjærgaard KD, Christiansen CF, Tietze IN, Hornstrup BG, Liem YS, Bangstrup M, Rantanen JM, Uhde M, Peters CD · 2026 · Kidney medicine · PMID 42890303
Saucereau J, Brenaut E, Ficheux AS, Rostoker G, Misery L, Le Gall-Ianotto C · 2026 · Renal failure · PMID 41708519
Mourani C, Kaur A, Jaoudeh PA, Reynolds B, Morin I, Enoiu M · 2026 · Pediatric nephrology (Berlin, Germany) · PMID 42895571
Müller S, Maintz L, Bieber T · 2024 · Allergy · PMID 38186219
Deeks ED · 2021 · Drugs · PMID 34674115
Fishbane S, Jamal A, Munera C, Wen W, Menzaghi F, KALM-1 Trial Investigators · 2020 · The New England journal of medicine · PMID 31702883
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All content on this page is for in-vitro research purposes only. Not intended for human or animal use. Consult a licensed professional before handling research chemicals. No content on this page constitutes medical advice or a treatment recommendation.
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