Setmelanotide
Also known as: RM-493 · imcivree · MC4R agonist
For in-vitro (laboratory) research purposes only. Not for human or animal consumption.
COMING SOONAvailable Forms
Research Applications
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For in-vitro research use only. Not for human consumption.
1What Is Setmelanotide?
MC4 receptor agonist studied for severe genetic obesity, particularly POMC and LEPR deficiencies.
4Published Research - Plain English Summaries
The studies below have been published in peer-reviewed journals. Summaries are written in plain language - no jargon. Citations are provided as text only.
Wabitsch M, Ulrich K, Denzer C · 2026 · Molecular and cellular pediatrics · PMID 42878773
Roth CL, Miller JL · 2026 · The New England journal of medicine · PMID 42874121
Ou Q, Tang J · 2026 · The New England journal of medicine · PMID 42874120
Zhang J, Zhan X, Li T · 2026 · The New England journal of medicine · PMID 42874119
Miller JL, van Santen HM, Phillips SA, Hamilton J, Aberle J, Sathyapalan T, Mohamed Z, McCormack SE, Shoemaker AH, Kelsey MM, Ghalib L, Stalla G · 2026 · The New England journal of medicine · PMID 42418774
Wabitsch M, Farooqi IS, Chung WK, van den Akker E, Kühnen P, Swain J, Garrison JC, Touchot N, Argente J, Clément K · 2026 · The Journal of clinical endocrinology and metabolism · PMID 42895739
Fox CK, Armstrong SC, Kelly AS · 2026 · JAMA · PMID 42905688
Delplanque J, Leloire A, Le Collen L, Loiselle H, Toussaint B, Vaillant E, Allegaert F, Beke T, Charpentier G, Franc S, Balkau B, Marre M · 2026 · Cell reports. Medicine · PMID 42849447
Fredrick TW, Camilleri M, Acosta A · 2025 · Clinical pharmacology : advances and applications · PMID 40995421
Roth CL, Scimia C, Shoemaker AH, Gottschalk M, Miller J, Yuan G, Malhotra S, Abuzzahab MJ · 2024 · The lancet. Diabetes & endocrinology · PMID 38697184
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All content on this page is for in-vitro research purposes only. Not intended for human or animal use. Consult a licensed professional before handling research chemicals. No content on this page constitutes medical advice or a treatment recommendation.
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